Long non-coding RNA ANRIL predicts poor prognosis and promotes invasion/metastasis in serous ovarian cancer
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چکیده
منابع مشابه
Long Non-coding RNA HOXA11 Antisense Promotes Cell Proliferation and Invasion and Predicts Patient Prognosis in Serous Ovarian Cancer
PURPOSE The biological function of long non-coding RNAs (lncRNAs) is only partially understood; therefore, in this study, we investigated the expression of the novel HOXA11 antisense (HOXA11as) lncRNA and its oncogenic role in serous ovarian cancer (SOC). MATERIALS AND METHODS HOXA11as expression was examined in 129 SOC tissue samples by real time reverse transcription polymerase chain reacti...
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Emerging evidence implicates that a large fraction of human genome was transcribed but the transcripts known as long non coding RNA are not translated into proteins. They are contributing in different cellular processes, including cellular proliferation and apoptosis. LncRNAs were found to play critical roles in many diseases and act as key regulators in malignancies. In this study, we investig...
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BACKGROUND Emerging evidences indicate that dysregulated long non-coding RNAs (lncRNAs) are implicated in cancer tumorigenesis and progression. LncRNA ANRIL has been shown to promote the progression of gastric cancer. However, the role of lncRNA ANRIL in human non-small cell lung cancer (NSCLC) remains unclear. METHODS Expression of lncRNA ANRIL was analyzed in 87 NSCLC tissues and three lung...
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Long noncoding RNA (lncRNA) profiles in ovarian cancer (OC) remain largely unknown. In the present study, we screened AB073614 as a new candidate lncRNA which promotes development of OC, in two independent datasets (GSE18521 and GSE38666) from the Gene Expression Omnibus (GEO). The level of AB073614 was then detected in 75 paired OC tissues and adjacent normal tissues by qRT-PCR. Results showed...
متن کاملUp-regulation of the long non-coding RNA ANRIL indicates poor prognosis and promotes tumorigenesis in oral squamous cell carcinoma
Dysregulation of long non-coding RNAs (lncRNAs) plays a critical role in tumor progression. LncRNA antisense non-coding RNA in the INK4 locus (ANRIL) has been reported to promote tumor progression in numerous cancers. However, its expression and function in oral squamous cell carcinoma (OSCC) remain largely unclear. Herein, we investigated the expression and clinical significance of lncRNA ANRI...
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ژورنال
عنوان ژورنال: International Journal of Oncology
سال: 2015
ISSN: 1019-6439,1791-2423
DOI: 10.3892/ijo.2015.2943